Mouse anti-Human sapiens (Human) ENG Monoclonal Antibody — Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis.
| Uniprot No. | P17813 |
| Target Names | ENG |
| Species Reactivity | Mouse |
| Immunogen | Synthesized peptide derived from human CD105(Endoglin) |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | Non-conjugated |
| Isotype | IgG2b, Kappa |
| Clonality | Monoclonal |
| Applications | ELISA, IHC |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells.
Mouse anti-Human sapiens (Human) ENG Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications. Explore more Antibody products →
Applications: ELISA, IHC
Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830). Acts as a TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:21737454, PubMed:22347366, PubMed:23300529, PubMed:8370410). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529)
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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
