Mouse anti-Human sapiens (Human) HLA-C Monoclonal Antibody

Mouse anti-Human sapiens (Human) HLA-C Monoclonal Antibody

Mouse anti-Human sapiens (Human) HLA-C Monoclonal Antibody — recombinant protein.

SKU: BCREC-000701MA Category:
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Product Specifications

Uniprot No.P10321
Target NamesHLA-C
Species ReactivityMouse
ImmunogenRecombinant Human HLA-C protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG
ClonalityMonoclonal
ApplicationsELISA, WB
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

ALLELE C*15:02: Presents CMV epitope derived from UL83 CC (VVCAHELVC) to CD8-positive T cells, triggering T cell cytotoxic response.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Endoplasmic reticulum membrane (Single-pass membrane protein)
Tissue Specificity: Ubiquitous. Highly expressed in fetal extravillous trophoblasts in the decidua basalis (at protein level)
Disease Association: Psoriasis 1 (PSORS1) : A common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. [Disease susceptibility is associated with variants affecting the gene represented in this entry. Allele C*06:02 presents a melanocyte autoantigen ADAMTSL5 (VRSRRCLRL) to Valpha3S1/Vbeta13S1 TCR on CD8-positive T cells, and may trigger an autoimmune response against melanocytes]

Product Specifications

Mouse anti-Human sapiens (Human) HLA-C Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

ALLELE C*15:02: Presents CMV epitope derived from UL83 CC (VVCAHELVC) to CD8-positive T cells, triggering T cell cytotoxic response

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Endoplasmic reticulum membrane (Single-pass membrane protein)

Disease Association

Psoriasis 1 (PSORS1) : A common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. [Disease susceptibility is associated with variants affecting the gene represented in this entry. Allele C*06:02 presents a melanocyte autoantigen ADAMTSL5 (VRSRRCLRL) to Valpha3S1/Vbeta13S1 TCR on CD8-positive T cells, and may trigger an autoimmune response against melanocytes]

Tissue Specificity

Ubiquitous. Highly expressed in fetal extravillous trophoblasts in the decidua basalis (at protein level)

Subunit

(Microbial infection) Interacts with HTLV-1 p12I accessory protein

Gene: HLA-C  |  Organism: Homo sapiens  |  Synonyms: HLA-Cw; Human leukocyte antigen C
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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