Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody
Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody - Image 2
Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody - Image 3
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Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody

Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody — recombinant protein.

SKU: BCREC-000179MA Category:
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Product Specifications

Uniprot No.P18627
Target NamesLAG3
Species ReactivityMouse
ImmunogenRecombinant Human Lymphocyte activation gene 3 protein (29-450AA)
ConjugateNon-conjugated
IsotypeIgG1
ClonalityMonoclonal
ApplicationsELISA, WB, IHC, FC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Primarily expressed in activated T-cells and a subset of natural killer (NK) cells

Product Specifications

Mouse anti-Human sapiens (Human) LAG3 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB, IHC, FC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response

Subcellular Location

Secreted

Tissue Specificity

Primarily expressed in activated T-cells and a subset of natural killer (NK) cells

Subunit

Homodimer; laterally engages two MHC class II molecules (PubMed:35761082, PubMed:39671469). Interacts with CD3E; disrupting the association between CD3E and LCK, thereby preventing TCR activation (PubMed:40592325)

Gene: LAG3  |  Organism: Homo sapiens
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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