Function
Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.
Biological Context
Subcellular Location: Cell membrane (Single-pass type I membrane protein)
Tissue Specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus
Product Specifications
Mouse anti-Human sapiens (Human) PDCD1LG2 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications. Explore more CD proteins →









