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Mouse anti-Human sapiens (Human) TNFRSF17 Monoclonal Antibody

Mouse anti-Human sapiens (Human) TNFRSF17 Monoclonal Antibody — Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.

SKU: BCREC-000211MA Categories: ,

Product Specifications

Uniprot No.Q02223
Target NamesTNFRSF17
Species ReactivityMouse
ImmunogenRecombinant Human TNFRSF17 protein (1-54AA)
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeIgG2b
ClonalityMonoclonal
ApplicationsELISA, WB, IHC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

Biological Context

Subcellular Location: Cell membrane (Single-pass type III membrane protein); Endomembrane system (Single-pass type III membrane protein)
Tissue Specificity: Expressed in mature B-cells, but not in T-cells or monocytes
Disease Association: [A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2]

Product Specifications

Mouse anti-Human sapiens (Human) TNFRSF17 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB, IHC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK

Subcellular Location

Cell membrane (Single-pass type III membrane protein); Endomembrane system (Single-pass type III membrane protein)

Disease Association

[A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2]

Tissue Specificity

Expressed in mature B-cells, but not in T-cells or monocytes

Subunit

Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6

Gene: TNFRSF17  |  Organism: Homo sapiens  |  Synonyms: B-cell maturation protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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