Recombinant African swine fever virus Major structural protein p17 (Ba71V-107) Protein, African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV), in vitro E.coli expression system, N-terminal 10xHis-tagged, 19.2kDa, purity >85% as determined by SDS-PAGE.
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Recombinant African swine fever virus Major structural protein p17 (Ba71V-107) Protein

Recombinant African swine fever virus Major structural protein p17 (Ba71V-107) Protein — Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Purity >85%.

SKU: BCRECP-00723TM Categories: ,
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Product Specifications

Uniprot No.Q89424
Gene NamesBa71V-107
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-117aa
SpeciesAfrican swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV)
Tag InfoN-terminal 10xHis-tagged
Molecular weight19.2kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane. Required for the assembly of the capsid and icosahedral morphogenesis.

Biological Context

Subcellular Location: Virion membrane (Single-pass membrane protein); Host endoplasmic reticulum membrane (Single-pass membrane protein); Host Golgi apparatus membrane (Single-pass membrane protein)

Product Specifications

Recombinant African swine fever virus Major structural protein p17 (Ba71V-107) Protein is a recombinant protein from African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV), expressed in in vitro E.coli expression system, covering amino acids 1-117aa, with N-terminal 10xHis-tagged tag, molecular weight 19.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (PubMed:31624094). Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane (PubMed:31624094). Required for the assembly of the capsid and icosahedral morphogenesis (PubMed:20504920). Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE (PubMed:35844609)

Subcellular Location

Virion membrane (Single-pass membrane protein); Host endoplasmic reticulum membrane (Single-pass membrane protein); Host Golgi apparatus membrane (Single-pass membrane protein)

Subunit

Interacts with the minor capsid protein M1249L and with the hexon capsid protein p72 capsomers; these interactions form a rigid zipper structure that stabilizes the capsomers. Interacts with host STING1 (PubMed:35844609)

Organism: African swine fever virus (strain Badajoz 1971 Vero-adapted)
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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