Recombinant Bovine Mannose-binding protein C (MBL)

Recombinant Bovine Mannose-binding protein C (MBL) — Calcium-dependent lectin involved in innate immune defense. Purity >85%.

SKU: BCRECP-003362 Category:

Product Specifications

Product SkuBCRECP-003362
Product DescriptionRecombinant Bovine Mannose-binding protein C (MBL) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged. It contains 21-249aa. [Accession | O02659].
Uniprot No.O02659
Gene NamesMBL
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region21-249aa
SpeciesBos taurus (Bovine)
Tag InfoN-terminal 10xHis-tagged
Molecular weight26.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Bovine Mannose-binding protein C (MBL) is a recombinant protein from Bos taurus (Bovine), expressed in Baculovirus, covering amino acids 21-249aa, with N-terminal 10xHis-tagged tag, molecular weight 26.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity)

Subcellular Location

Secreted

Subunit

Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2 (By similarity). Interacts with MEP1A and MEP1B and may inhibit their catalytic activity (By similarity)

Gene: MBL  |  Organism: Bos taurus  |  Synonyms: Mannan-binding protein

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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