Function
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
Biological Context
Subcellular Location: Secreted
Product Specifications
Recombinant Bovine Mannose-binding protein C (MBL) is a recombinant protein from Bos taurus (Bovine), expressed in Baculovirus, covering amino acids 21-249aa, with N-terminal 10xHis-tagged tag, molecular weight 26.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
