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Recombinant Candida albicans Secreted aspartic protease 6 (SAP6)

Recombinant Candida albicans Secreted aspartic protease 6 (SAP6) — Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors. Purity >85%.

SKU: BCRECP-004372 Categories: , ,

Product Specifications

Product SkuBCRECP-004372
Product DescriptionRecombinant Candida albicans Secreted aspartic protease 6 (SAP6) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 77-418aa. [Accession | P43095].
Uniprot No.P43095
Gene NamesSAP6
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region77-418aa
SpeciesCandida albicans (Yeast)
Tag InfoN-terminal 6xHis-tagged
Molecular weight39.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors. These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense. Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Candida albicans Secreted aspartic protease 6 (SAP6) is a recombinant protein from Candida albicans (Yeast), expressed in E.coli, covering amino acids 77-418aa, with N-terminal 6xHis-tagged tag, molecular weight 39.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors (PubMed:11478679, PubMed:12065511, PubMed:17652724, PubMed:20713630, PubMed:21540243, PubMed:22302440). These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense (PubMed:11478679, PubMed:12065511, PubMed:17652724, PubMed:20713630, PubMed:21540243, PubMed:22302440). Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein (PubMed:23927842)

Subcellular Location

Secreted

Gene: SAP6  |  Organism: Candida albicans  |  Synonyms: Candidapepsin-6
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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