Function
Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Product Specifications
Recombinant Human TNFRSF1A Protein is a recombinant protein, expressed in Baculovirus-Insect Cells, covering amino acids 30-211aa, with N-6His tag, molecular weight 47.7kDa (424aa), 57-70KDa (SDS-PAGE under reducing conditions.), purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more TNF Family proteins →
