Recombinant Dog Angiopoietin-1 (ANGPT1) — Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Purity >85%.
| Product Sku | BCRECP-002087 |
| Product Description | Recombinant Dog Angiopoietin-1 (ANGPT1) Protein is expressed from Mammalian cell with C-terminal 6xHis-tagged. It contains 20-497aa. [Accession | Q60FC1]. |
| Uniprot No. | Q60FC1 |
| Gene Names | ANGPT1 |
| Purity | Greater than 85% as determined by SDS-PAGE. |
| Expression System | Mammalian cell |
| Expression Region | 20-497aa |
| Species | Canis lupus familiaris (Dog) (Canis familiaris) |
| Tag Info | C-terminal 6xHis-tagged |
| Molecular weight | 58.8kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Cancer |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF.
Recombinant Dog Angiopoietin-1 (ANGPT1) — Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Purity >85%. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Please contact us to obtain bioactivity data.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development (By similarity)
Secreted
Homooligomer (By similarity). Interacts with TEK/TIE2 (By similarity). Interacts with SVEP1/polydom (By similarity). Interacts with THBD; this interaction significantly inhibits the generation of activated PC and TAFIa/CPB2 by the thrombin/thrombomodulin complex (By similarity)
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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.
Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.
Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.
