Recombinant Dog C-C motif chemokine 17 (CCL17), Canis lupus familiaris (Dog) (Canis familiaris), Yeast, C-terminal 6xHis-tagged, 10.1kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Dog C-C motif chemokine 17 (CCL17)

Recombinant Dog C-C motif chemokine 17 (CCL17) — Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Purity >85%.

SKU: BCRECP-002305 Categories: ,
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Product Specifications

Product SkuBCRECP-002305
Product DescriptionRecombinant Dog C-C motif chemokine 17 (CCL17) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 24-99aa. [Accession | Q95N01].
Uniprot No.Q95N01
Gene NamesCCL17
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region24-99aa
SpeciesCanis lupus familiaris (Dog) (Canis familiaris)
Tag InfoC-terminal 6xHis-tagged
Molecular weight10.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in thymus, spleen, lymph node, lung and heart

Product Specifications

Recombinant Dog C-C motif chemokine 17 (CCL17) is a recombinant protein from Canis lupus familiaris (Dog) (Canis familiaris), expressed in Yeast, covering amino acids 24-99aa, with C-terminal 6xHis-tagged tag, molecular weight 10.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation (By similarity). In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Expressed in thymus, spleen, lymph node, lung and heart

Gene: CCL17  |  Organism: Canis lupus familiaris  |  Synonyms: CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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