Recombinant Dog C-C motif chemokine 17 (CCL17), Canis lupus familiaris (Dog) (Canis familiaris), Yeast, C-terminal 6xHis-tagged, 10.1kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Dog C-C motif chemokine 17 (CCL17)

Recombinant Dog C-C motif chemokine 17 (CCL17) — Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Purity >85%.

SKU: BCRECP-002305 Categories: ,
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Product Specifications

Product SkuBCRECP-002305
Product DescriptionRecombinant Dog C-C motif chemokine 17 (CCL17) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 24-99aa. [Accession | Q95N01].
Uniprot No.Q95N01
Gene NamesCCL17
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region24-99aa
SpeciesCanis lupus familiaris (Dog) (Canis familiaris)
Tag InfoC-terminal 6xHis-tagged
Molecular weight10.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in thymus, spleen, lymph node, lung and heart

Product Specifications

Recombinant Dog C-C motif chemokine 17 (CCL17) is a recombinant protein from Canis lupus familiaris (Dog) (Canis familiaris), expressed in Yeast, covering amino acids 24-99aa, with C-terminal 6xHis-tagged tag, molecular weight 10.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation (By similarity). In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Expressed in thymus, spleen, lymph node, lung and heart

Gene: CCL17  |  Organism: Canis lupus familiaris  |  Synonyms: CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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