Function
Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
Biological Context
Subcellular Location: Nucleus
Product Specifications
Recombinant Drosophila mauritiana Mariner Mos1 transposase (marinerT) is a recombinant protein from Drosophila mauritiana (Fruit fly), expressed in E.coli, covering amino acids 1-345aa, with C-terminal 6xHis-tagged tag, molecular weight 47.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
