Recombinant Escherichia coli Translational regulator CsrA (csrA)

Recombinant Escherichia coli Translational regulator CsrA (csrA) — A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Purity >85%.

SKU: BCRECP-002463 Category:

Product Specifications

Product SkuBCRECP-002463
Product DescriptionRecombinant Escherichia coli Translational regulator CsrA (csrA) Protein is expressed from E.coli with Tag-Free. It contains 1-61aa. [Accession | B1XCM4].
Uniprot No.B1XCM4
Gene NamescsrA
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-61aa
SpeciesEscherichia coli (strain K12 / DH10B)
Tag InfoTag-Free
Molecular weight6.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.

Biological Context

Subcellular Location: Cytoplasm

Product Specifications

Recombinant Escherichia coli Translational regulator CsrA (csrA) is a recombinant protein from Escherichia coli (strain K12 / DH10B), expressed in E.coli, covering amino acids 1-61aa, with Tag-Free tag, molecular weight 6.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s)

Subcellular Location

Cytoplasm

Subunit

Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core

Gene: csrA  |  Organism: Escherichia coli (strain K12 / DH10B)  |  Synonyms: Carbon storage regulator

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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