Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial, Gorilla gorilla gorilla (Western lowland gorilla), E.coli, C-terminal 6xHis-tagged, 15.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial — G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Purity >85%.

SKU: BCRECP-003019 Category:
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Product Specifications

Product SkuBCRECP-003019
Product DescriptionRecombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 290-359aa. [Accession | Q76MS7].
Uniprot No.Q76MS7
Gene NamesHRH2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region290-359aa
SpeciesGorilla gorilla gorilla (Western lowland gorilla)
Tag InfoC-terminal 6xHis-tagged
Molecular weight15.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels. This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Gorilla gorilla gorilla Histamine H2 receptor (HRH2), partial is a recombinant protein from Gorilla gorilla gorilla (Western lowland gorilla), expressed in E.coli, covering amino acids 290-359aa, with C-terminal 6xHis-tagged tag, molecular weight 15.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

G protein-coupled receptor for histamine, primarily mediating gastric acid secretion. Predominantly expressed in the gastric mucosa, couples to G(s) G alpha proteins upon histamine binding, leading to activation of adenylate cyclase and increased intracellular cyclic AMP (cAMP) levels (By similarity). This signaling cascade stimulates parietal cells to secrete hydrochloric acid, playing a key role in digestive physiology. Also expressed in other tissues, including the heart and central nervous system, where it may contribute to cardiac stimulation and modulate neurotransmitter release (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

Interacts with GNAS

Gene: HRH2  |  Organism: Gorilla gorilla gorilla  |  Synonyms: Gastric receptor I

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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