Recombinant Human 14-3-3 protein eta (YWHAH), partial, Homo sapiens (Human), E.coli, N-terminal GST-tagged, 54.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human 14-3-3 protein eta (YWHAH), partial

Recombinant Human 14-3-3 protein eta (YWHAH), partial — Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Purity >90%.

SKU: BCRECP-001928 Category:
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Product Specifications

Product SkuBCRECP-001928
Product DescriptionRecombinant Human 14-3-3 protein eta (YWHAH) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 4-246aa. [Accession | Q04917].
Uniprot No.Q04917
Gene NamesYWHAH
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region4-246aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight54.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Biological Context

Tissue Specificity: Expressed mainly in the brain and present in other tissues albeit at lower levels

Product Specifications

Recombinant Human 14-3-3 protein eta (YWHAH), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 4-246aa, with N-terminal GST-tagged tag, molecular weight 54.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1

Tissue Specificity

Expressed mainly in the brain and present in other tissues albeit at lower levels

Subunit

Homodimer (By similarity). Interacts with many nuclear hormone receptors and cofactors including AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP and THRA. Interacts with ABL1 (phosphorylated form); the interaction retains it in the cytoplasm. Interacts with ARHGEF28 and CDK16 (By similarity). Weakly interacts with CDKN1B. Interacts with GAB2. Interacts with KCNK18 in a phosphorylation-dependent manner. Interacts with SAMSN1 (By similarity). Interacts with the 'Ser-241' phosphorylated form of PDPK1. Interacts with the 'Thr-369' phosphorylated form of DAPK2 (PubMed:26047703). Interacts with PI4KB, TBC1D22A and TBC1D22B (PubMed:23572552). Interacts with SLITRK1 (PubMed:19640509). Interacts with MEFV (PubMed:27030597)

Gene: YWHAH  |  Organism: Homo sapiens  |  Synonyms: Protein AS1
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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