Function
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
Biological Context
Subcellular Location: Endoplasmic reticulum; Golgi apparatus
Tissue Specificity: Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart
Product Specifications
Recombinant Human Acyl-CoA-binding protein (DBI) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2-104aa, with N-terminal 6xHis-tagged tag, molecular weight 15.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
