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Recombinant Human Adenine phosphoribosyltransferase (APRT)

Recombinant Human Adenine phosphoribosyltransferase (APRT) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000115 Categories: ,

Product Specifications

Product SkuBCRECP-000115
Product DescriptionRecombinant Human Adenine phosphoribosyltransferase (APRT) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-180aa. [Accession | P07741].
Uniprot No.P07741
Gene NamesAPRT
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-180aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight46.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

Biological Context

Subcellular Location: Cytoplasm
Disease Association: Adenine phosphoribosyltransferase deficiency (APRTD) : An enzymatic deficiency that can lead to urolithiasis and renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones. [The disease is caused by variants affecting the gene represented in this entry]
Pathway: Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1

Product Specifications

Recombinant Human Adenine phosphoribosyltransferase (APRT) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-180aa, with N-terminal GST-tagged tag, molecular weight 46.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis

Subcellular Location

Cytoplasm

Disease Association

Adenine phosphoribosyltransferase deficiency (APRTD) : An enzymatic deficiency that can lead to urolithiasis and renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones. [The disease is caused by variants affecting the gene represented in this entry]

Subunit

Homodimer

Pathway

Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1

Gene: APRT  |  Organism: Homo sapiens
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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