Recombinant Human ALK and LTK ligand 1 (ALKAL1), Homo sapiens (Human), Baculovirus, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 15.4kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human ALK and LTK ligand 1 (ALKAL1)

Recombinant Human ALK and LTK ligand 1 (ALKAL1) — Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation. Purity >85%.

SKU: BCRECP-000061 Category:
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Product Specifications

Product SkuBCRECP-000061
Product DescriptionRecombinant Human ALK and LTK ligand 1 (ALKAL1) Protein is expressed from Baculovirus with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 28-129aa. [Accession | Q6UXT8].
Uniprot No.Q6UXT8
Gene NamesALKAL1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region28-129aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight15.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation. Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation. In contrast to ALKAL2, does not act as a potent physiological ligand for ALK.

Biological Context

Subcellular Location: Secreted; Cell membrane
Tissue Specificity: Widely expressed with highest levels in thyroid and moderate levels in stomach, trachea, small intestine, prostate and brain

Product Specifications

Recombinant Human ALK and LTK ligand 1 (ALKAL1) is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 28-129aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 15.4kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation (PubMed:25331893, PubMed:26418745, PubMed:26630010, PubMed:34646012, PubMed:34819673). Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation (PubMed:34646012, PubMed:34819673). In contrast to ALKAL2, does not act as a potent physiological ligand for ALK (PubMed:26418745, PubMed:34646012)

Subcellular Location

Secreted; Cell membrane

Tissue Specificity

Widely expressed with highest levels in thyroid and moderate levels in stomach, trachea, small intestine, prostate and brain

Gene: ALKAL1  |  Organism: Homo sapiens  |  Synonyms: Augmentor beta
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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