Recombinant Human Allograft inflammatory factor 1 (AIF1)

Recombinant Human Allograft inflammatory factor 1 (AIF1) — Actin-binding protein that enhances membrane ruffling and RAC activation. Purity >90%.

SKU: BCRECP-000048 Category:

Product Specifications

Product SkuBCRECP-000048
Product DescriptionRecombinant Human Allograft inflammatory factor 1 (AIF1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 2-147aa. [Accession | P55008].
Uniprot No.P55008
Gene NamesAIF1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-147aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight32.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium.

Biological Context

Subcellular Location: Cytoplasm, cytoskeleton; Cell projection, ruffle membrane (Peripheral membrane protein); Cell projection, phagocytic cup
Tissue Specificity: Detected in T-lymphocytes and peripheral blood mononuclear cells

Product Specifications

Recombinant Human Allograft inflammatory factor 1 (AIF1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2-147aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 32.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation

Subcellular Location

Cytoplasm, cytoskeleton; Cell projection, ruffle membrane (Peripheral membrane protein); Cell projection, phagocytic cup

Tissue Specificity

Detected in T-lymphocytes and peripheral blood mononuclear cells

Subunit

Homodimer (Potential). Monomer. Interacts with LCP1

Gene: AIF1  |  Organism: Homo sapiens  |  Synonyms: Ionized calcium-binding adapter molecule 1; Protein G1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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