Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 34.6 kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active)

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >85%.

SKU: BCACP-000619 Category:
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Product SKUBCACP-000619
Product DescriptionRecombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-291aa. [Accession | P07306].
Uniprot No.P07306
Gene NamesASGR1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-291aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight34.6 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Mouse Tnfsf4 at 4 μg/mL can bind Mouse Tnfrsf4. The EC50 is 3.581-4.060 ng/mL.;Mouse Tnfrsf4 captured on Protein A Chip can bind Recombinant Mouse Tnfsf4 with an affinity constant of 0.438 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesAsialoglycoprotein receptor 1; ASGP-R 1; ASGPR 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1

Function

(Microbial infection) Plays an essential role in ACE2-independent SARS-CoV-2 entry by acting as alternate receptor.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed exclusively in hepatic parenchymal cells

Product Specifications

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-291aa, with C-terminal 10xHis-tagged tag, molecular weight 34.6 kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Tnfsf4 at 4 μg/mL can bind Mouse Tnfrsf4. The EC50 is 3.581-4.060 ng/mL.;Mouse Tnfrsf4 captured on Protein A Chip can bind Recombinant Mouse Tnfsf4 with an affinity constant of 0.438 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

(Microbial infection) Plays an essential role in ACE2-independent SARS-CoV-2 entry by acting as alternate receptor

Subcellular Location

Secreted

Tissue Specificity

Expressed exclusively in hepatic parenchymal cells

Subunit

(Microbial infection) Interacts with SARS-CoV-2 virus spike glycoprotein

Gene: ASGR1  |  Organism: Homo sapiens  |  Synonyms: C-type lectin domain family 4 member H1; Hepatic lectin H1
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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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