Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial — Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Purity >90%.
| Product Sku | BCRECP-001264 |
| Product Description | Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2) Protein is expressed from E.coli with C-terminal 12xHis-tagged. It contains 23-458aa. [Accession | P20594]. |
| Uniprot No. | P20594 |
| Gene Names | NPR2 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Expression System | E.coli |
| Expression Region | 23-458aa |
| Species | Homo sapiens (Human) |
| Tag Info | C-terminal 12xHis-tagged |
| Molecular weight | 50.3kDa |
| Activity | Please contact us to obtain bioactivity data. |
| Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose. |
| Storage | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Research Areas | Cardiovascular |
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand.
Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial — Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Purity >90%. Suitable for ELISA and Western Blot applications.
SDS-PAGE: Single band at expected molecular weight confirming purity.
ELISA: Suitable as coating antigen or detection standard.
Western Blot: Compatible with standard Western Blot protocols.
Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.
Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.
Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.
Shelf Life: 12 months from date of receipt when stored as recommended.
Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth
Cell membrane (Single-pass type I membrane protein)
Acromesomelic dysplasia 1 (AMD1) : A form of acromesomelic dysplasia, a skeletal disorder characterized by short stature, very short limbs and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMD1 is an autosomal recessive form characterized by axial skeletal involvement with wedging of vertebral bodies. All skeletal elements are present but show abnormal rates of linear growth. [The disease is caused by variants affecting the gene represented in this entry] | Epiphyseal chondrodysplasia, Miura type (ECDM) : An overgrowth syndrome characterized by tall stature, long hands and feet with arachnodactyly, macrodactyly of the great toes, scoliosis, coxa valga and slipped capital femoral epiphysis. [The disease is caused by variants affecting the gene represented in this entry] | Short stature with non-specific skeletal abnormalities 1 (SNSK1) : An autosomal dominant condition characterized by short stature, defined as a height less than 2 SD below normal, and no endocrine abnormalities. Some SNSK1 patients show delayed bone age. [The disease is caused by variants affecting the gene represented in this entry]
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Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.
Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.
Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.
