Recombinant Human Augurin(ECRG4), partial

Recombinant Human Augurin(ECRG4), partial — Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. Purity >85%.

SKU: BCRECP-000556 Category:

Product Specifications

Product SkuBCRECP-000556
Product DescriptionRecombinant Human Augurin(ECRG4) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 71-132aa. [Accession | Q9H1Z8].
Uniprot No.Q9H1Z8
Gene NamesECRG4
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region71-132aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight20.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.

Biological Context

Subcellular Location: Secreted; Cytoplasm; Apical cell membrane
Tissue Specificity: Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level)

Product Specifications

Recombinant Human Augurin(ECRG4), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 71-132aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 20.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity)

Subcellular Location

Secreted; Cytoplasm; Apical cell membrane

Tissue Specificity

Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level)

Gene: ECRG4  |  Organism: Homo sapiens  |  Synonyms: Esophageal cancer-related gene 4 protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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