Function
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
Biological Context
Subcellular Location: Secreted
Disease Association: Ovarian dysgenesis 2 (ODG2) : A disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads. [The disease is caused by variants affecting the gene represented in this entry] | Premature ovarian failure 4 (POF4) : An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Bone morphogenetic protein 15 (BMP15) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 268-392aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 21.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
