Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9), partial, Homo sapiens (Human), Baculovirus, C-terminal 6xHis-tagged, 15.8kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9), partial

Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9), partial — The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Purity >95%.

SKU: BCRECP-001686 Categories: , ,
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Product Specifications

Product SkuBCRECP-001686
Product DescriptionRecombinant Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) Protein is expressed from Baculovirus with C-terminal 6xHis-tagged. It contains 408-534aa. [Accession | O60271].
Uniprot No.O60271
Gene NamesSPAG9
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemBaculovirus
Expression Region408-534aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight15.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasDevelopmental Biology

Function

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking.

Biological Context

Subcellular Location: Cytoplasmic vesicle, secretory vesicle, acrosome
Tissue Specificity: Expressed in testis

Product Specifications

Recombinant Human C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9), partial is a recombinant protein from Homo sapiens (Human), expressed in Baculovirus, covering amino acids 408-534aa, with C-terminal 6xHis-tagged tag, molecular weight 15.8kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module (PubMed:14743216). Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex (PubMed:29146937). Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking (By similarity)

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, acrosome

Tissue Specificity

Expressed in testis

Subunit

Interacts with MAPK8, MAPK9, MAPK10

Gene: SPAG9  |  Organism: Homo sapiens  |  Synonyms: Cancer/testis antigen 89; Human lung cancer oncogene 6 protein; JNK-associated leucine-zipper protein; Mitogen-activated protein kinase 8-interacting protein 4; Proliferation-inducing protein 6; Protein highly expressed in testis; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1
Key Publications

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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