Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 47.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) — Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Purity >90%.

SKU: BCRECP-000341 Category:
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Product Specifications

Product SkuBCRECP-000341
Product DescriptionRecombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 35-320aa. [Accession | P40199].
Uniprot No.P40199
Gene NamesCEACAM6
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region35-320aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight47.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasTags & Cell Markers

Function

Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8.

Biological Context

Subcellular Location: Cell membrane (Lipid-anchor, GPI-anchor); Apical cell membrane; Cell surface
Tissue Specificity: Expressed in neutrophils. Expressed in columnar epithelial and goblet cells of the colon. Expressed in numerous tumor cell lines (at protein level)

Product Specifications

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 35-320aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 47.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:10910050, PubMed:11590190, PubMed:1378450, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:16204051, PubMed:2022629). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8 (PubMed:11590190, PubMed:16204051, PubMed:2022629, PubMed:2803308, PubMed:8776764). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450). Plays a role in cell migration and cell adhesion to endothelial cells (PubMed:16204051)

Subcellular Location

Cell membrane (Lipid-anchor, GPI-anchor); Apical cell membrane; Cell surface

Tissue Specificity

Expressed in neutrophils (PubMed:1378450). Expressed in columnar epithelial and goblet cells of the colon (PubMed:10436421). Expressed in numerous tumor cell lines (at protein level) (PubMed:16204051)

Subunit

Homodimer; homodimerizes via its Ig-like V-type domain. Heterodimer with CEACAM8; heterodimerizes via its Ig-like V-type domain

Gene: CEACAM6  |  Organism: Homo sapiens  |  Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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