Recombinant Human CD44 antigen (CD44) (Δ507-536), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 78.8kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human CD44 antigen (CD44) (Δ507-536), partial

Recombinant Human CD44 antigen (CD44) (Δ507-536), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >85%.

SKU: BCRECP-000294 Categories: ,
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Product Specifications

Product SkuBCRECP-000294
Product DescriptionRecombinant Human CD44 antigen (CD44) (Δ507-536) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 21-649aa(Δ507-536). [Accession | P16070].
Uniprot No.P16070
Gene NamesCD44
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region21-649aa(Δ507-536)
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight78.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

(Microbial infection) Promotes foot-and-mouth disease virus internalization via macropinocytosis.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cell projection, microvillus; Secreted
Tissue Specificity: Detected in fibroblasts and urine (at protein level). Detected in placenta (at protein level). Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells

Product Specifications

Recombinant Human CD44 antigen (CD44) (Δ507-536), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 21-649aa(Δ507-536), with N-terminal 6xHis-SUMO-tagged tag, molecular weight 78.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

(Microbial infection) Promotes foot-and-mouth disease virus internalization via macropinocytosis

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell projection, microvillus; Secreted

Tissue Specificity

Detected in fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Detected in placenta (at protein level) (PubMed:32337544). Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells

Subunit

(Microbial infection) Interacts with foot-and-mouth disease virus protein VP3; this interaction allows FMDV entry into host cell via macropinocytosis

Gene: CD44  |  Organism: Homo sapiens  |  Synonyms: CDw44; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; Phagocytic glycoprotein I
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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