Recombinant Human CD81 antigen (CD81), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 38.7kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human CD81 antigen (CD81), partial

Recombinant Human CD81 antigen (CD81), partial — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >85%.

SKU: BCRECP-000313 Categories: ,
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Product Specifications

Product SkuBCRECP-000313
Product DescriptionRecombinant Human CD81 antigen (CD81) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 113-201aa. [Accession | P60033].
Uniprot No.P60033
Gene NamesCD81
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region113-201aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight38.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

(Microbial infection) Specifically required for Plasmodium falciparum infectivity of hepatocytes, controlling sporozoite entry into hepatocytes via the parasitophorous vacuole and subsequent parasite differentiation to exoerythrocytic forms.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Basolateral cell membrane (Multi-pass membrane protein)
Tissue Specificity: Expressed on B cells (at protein level). Expressed in hepatocytes (at protein level). Expressed in monocytes/macrophages (at protein level). Expressed on both naive and memory CD4-positive T cells (at protein level)
Disease Association: Immunodeficiency, common variable, 6 (CVID6) : A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human CD81 antigen (CD81), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 113-201aa, with C-terminal hFc1-tagged tag, molecular weight 38.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

(Microbial infection) Specifically required for Plasmodium falciparum infectivity of hepatocytes, controlling sporozoite entry into hepatocytes via the parasitophorous vacuole and subsequent parasite differentiation to exoerythrocytic forms

Subcellular Location

Cell membrane (Multi-pass membrane protein); Basolateral cell membrane (Multi-pass membrane protein)

Disease Association

Immunodeficiency, common variable, 6 (CVID6) : A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed on B cells (at protein level) (PubMed:20237408). Expressed in hepatocytes (at protein level) (PubMed:12483205). Expressed in monocytes/macrophages (at protein level) (PubMed:12796480). Expressed on both naive and memory CD4-positive T cells (at protein level) (PubMed:22307619)

Subunit

(Microbial infection) Plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer

Gene: CD81  |  Organism: Homo sapiens  |  Synonyms: 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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