Recombinant Human Claudin-1 (CLDN1)-Detergent (Active), Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-flag tagged, 25.1 kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Claudin-1 (CLDN1)-Detergent (Active)

Recombinant Human Claudin-1 (CLDN1)-Detergent (Active) — (Microbial infection) Acts as a co-receptor for hepatitis C virus (HCV) in hepatocytes. Purity >85%.

SKU: BCACP-000574 Category:
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Product SKUBCACP-000574
Product DescriptionRecombinant Human Claudin-1 (CLDN1)-Detergent protein is expressed from Mammalian cell with N-terminal 10xHis-flag tagged. It contains 2-211aa. [Accession | O95832].
Uniprot No.O95832
Gene NamesCLDN1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region2-211aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-flag tagged
Molecular weight25.1 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human CD5 at 2 μg/mL can bind Anti-CD5 recombinant antibody .The EC50 is 0.9640-1.171 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesSenescence-associated epithelial membrane protein; CLDN1; CLD1, SEMP1; UNQ481/PRO944

Function

(Microbial infection) Acts as a co-receptor for hepatitis C virus (HCV) in hepatocytes. Associates with CD81 and the CLDN1-CD81 receptor complex is essential for HCV entry into host cell. Acts as a receptor for dengue virus.

Product Specifications

Recombinant Human Claudin-1 (CLDN1)-Detergent (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 2-211aa, with N-terminal 10xHis-flag tagged tag, molecular weight 25.1 kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human CD5 at 2 μg/mL can bind Anti-CD5 recombinant antibody .The EC50 is 0.9640-1.171 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Acts as a co-receptor for hepatitis C virus (HCV) in hepatocytes (PubMed:17325668, PubMed:20375010, PubMed:24038151). Associates with CD81 and the CLDN1-CD81 receptor complex is essential for HCV entry into host cell (PubMed:20375010). Acts as a receptor for dengue virus (PubMed:24074594)

Gene: CLDN1  |  Organism: Homo sapiens

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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