Recombinant Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 39.0kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1), partial

Recombinant Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1), partial — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCRECP-000248 Categories: ,
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Product Specifications

Product SkuBCRECP-000248
Product DescriptionRecombinant Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 159-250aa. [Accession | Q6UXH8].
Uniprot No.Q6UXH8
Gene NamesCCBE1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region159-250aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight39.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Detected in fibroblasts and urine (at protein level). Not expressed in blood or lymphatic endothelial cells
Disease Association: Hennekam lymphangiectasia-lymphedema syndrome 1 (HKLLS1) : A form of Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and some manifest intellectual disability. HKLLS1 inheritance is autosomal recessive. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 159-250aa, with C-terminal hFc1-tagged tag, molecular weight 39.0kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis

Subcellular Location

Secreted

Disease Association

Hennekam lymphangiectasia-lymphedema syndrome 1 (HKLLS1) : A form of Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and some manifest intellectual disability. HKLLS1 inheritance is autosomal recessive. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Detected in fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Not expressed in blood or lymphatic endothelial cells

Gene: CCBE1  |  Organism: Homo sapiens  |  Synonyms: Full of fluid protein homolog
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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