Recombinant Human Collagen triple helix repeat-containing protein 1 (CTHRC1), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 52kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Collagen triple helix repeat-containing protein 1 (CTHRC1)

Recombinant Human Collagen triple helix repeat-containing protein 1 (CTHRC1) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCRECP-000447 Category:
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Product Specifications

Product SkuBCRECP-000447
Product DescriptionRecombinant Human Collagen triple helix repeat-containing protein 1 (CTHRC1) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 31-243aa. [Accession | Q96CG8].
Uniprot No.Q96CG8
Gene NamesCTHRC1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region31-243aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight52kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Migration

Function

May act as a negative regulator of collagen matrix deposition.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix
Tissue Specificity: Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells
Disease Association: Barrett esophagus (BE) : A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. [Disease susceptibility is associated with variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Collagen triple helix repeat-containing protein 1 (CTHRC1) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 31-243aa, with C-terminal hFc1-tagged tag, molecular weight 52kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May act as a negative regulator of collagen matrix deposition

Subcellular Location

Secreted, extracellular space, extracellular matrix

Disease Association

Barrett esophagus (BE) : A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. [Disease susceptibility is associated with variants affecting the gene represented in this entry]

Tissue Specificity

Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells

Gene: CTHRC1  |  Organism: Homo sapiens
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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