Recombinant Human Collectin-10 (COLEC10), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 43.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Collectin-10 (COLEC10)

Recombinant Human Collectin-10 (COLEC10) — Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Purity >90%.

SKU: BCRECP-000408 Category:
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Product Specifications

Product SkuBCRECP-000408
Product DescriptionRecombinant Human Collectin-10 (COLEC10) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 28-277aa. [Accession | Q9Y6Z7].
Uniprot No.Q9Y6Z7
Gene NamesCOLEC10
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region28-277aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight43.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration.

Biological Context

Subcellular Location: Secreted; Golgi apparatus; Cytoplasm
Tissue Specificity: Highly expressed in liver, placenta and adrenal gland. Moderately expressed in small intestine, lung, stomach and prostate. Weakly expressed in trachea and spleen
Disease Association: 3MC syndrome 3 (3MC3) : A form of 3MC syndrome, an autosomal recessive disorder characterized by facial dysmorphism, craniosynostosis, learning disability, and genital, limb and vesicorenal anomalies. Facial features include hypertelorism, blepharophimosis, blepharoptosis and highly arched eyebrows, cleft lip and/or palate. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Collectin-10 (COLEC10) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 28-277aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 43.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine (PubMed:10224141). Acts as a chemoattractant, probably involved in the regulation of cell migration (PubMed:28301481)

Subcellular Location

Secreted; Golgi apparatus; Cytoplasm

Disease Association

3MC syndrome 3 (3MC3) : A form of 3MC syndrome, an autosomal recessive disorder characterized by facial dysmorphism, craniosynostosis, learning disability, and genital, limb and vesicorenal anomalies. Facial features include hypertelorism, blepharophimosis, blepharoptosis and highly arched eyebrows, cleft lip and/or palate. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Highly expressed in liver, placenta and adrenal gland. Moderately expressed in small intestine, lung, stomach and prostate. Weakly expressed in trachea and spleen

Gene: COLEC10  |  Organism: Homo sapiens  |  Synonyms: Collectin liver protein 1; Collectin-34

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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