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Recombinant Human Corticosteroid-binding globulin (SERPINA6)

Recombinant Human Corticosteroid-binding globulin (SERPINA6) — recombinant protein from Homo sapiens (Human), expressed in Yeast. Purity >90%.

Product Specifications

Product SkuBCRECP-001612
Product DescriptionRecombinant Human Corticosteroid-binding globulin (SERPINA6) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 23-405aa. [Accession | P08185].
Uniprot No.P08185
Gene NamesSERPINA6
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region23-405aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight44.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasTransport

Function

Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells
Disease Association: Corticosteroid-binding globulin deficiency (CBG deficiency) : Extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Corticosteroid-binding globulin (SERPINA6) is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 23-405aa, with N-terminal 6xHis-tagged tag, molecular weight 44.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species

Subcellular Location

Secreted

Disease Association

Corticosteroid-binding globulin deficiency (CBG deficiency) : Extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells

Gene: SERPINA6  |  Organism: Homo sapiens  |  Synonyms: Serpin A6; Transcortin
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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