Function
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells
Disease Association: Corticosteroid-binding globulin deficiency (CBG deficiency) : Extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Corticosteroid-binding globulin (SERPINA6) is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 23-405aa, with N-terminal 6xHis-tagged tag, molecular weight 44.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Immune Checkpoint proteins →
