Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 (ATF7), partial

Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 (ATF7), partial — Acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. Purity >95%.

SKU: BCRECP-000128 Category:

Product Specifications

Product SkuBCRECP-000128
Product DescriptionRecombinant Human Cyclic AMP-dependent transcription factor ATF-7 (ATF7) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-117aa. [Accession | P17544].
Uniprot No.P17544
Gene NamesATF7
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-117aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight19.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.

Biological Context

Subcellular Location: Cytoplasm
Tissue Specificity: Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung

Product Specifications

Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 (ATF7), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-117aa, with C-terminal 6xHis-tagged tag, molecular weight 19.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation

Subcellular Location

Cytoplasm

Tissue Specificity

Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung

Subunit

(Microbial infection) Interacts with adenovirus 2 E1A; the interaction enhances the ATF7-mediated viral transactivation activity which requires the zinc-binding domains of both E1A and ATF7

Gene: ATF7  |  Organism: Homo sapiens  |  Synonyms: Activating transcription factor 7; Transcription factor ATF-A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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