Function
Acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Biological Context
Subcellular Location: Cytoplasm
Tissue Specificity: Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung
Product Specifications
Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 (ATF7), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-117aa, with C-terminal 6xHis-tagged tag, molecular weight 19.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
