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Recombinant Human cytomegalovirus Protein UL16 (UL16), partial

Recombinant Human cytomegalovirus Protein UL16 (UL16), partial — Plays a role in escape from host immune response. Purity >90%.

SKU: BCRECP-004681 Categories: ,

Product Specifications

Product SkuBCRECP-004681
Product DescriptionRecombinant Human cytomegalovirus Protein UL16 (UL16) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 27-184aa. [Accession | P16757].
Uniprot No.P16757
Gene NamesUL16
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region27-184aa
SpeciesHuman cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Tag InfoC-terminal 6xHis-tagged
Molecular weight19.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Plays a role in escape from host immune response. Blocks the interaction between the host KLRK1 receptor with the ligands ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines.

Biological Context

Subcellular Location: Host membrane (Single-pass membrane protein)

Product Specifications

Recombinant Human cytomegalovirus Protein UL16 (UL16), partial is a recombinant protein from Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5), expressed in Yeast, covering amino acids 27-184aa, with C-terminal 6xHis-tagged tag, molecular weight 19.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Plays a role in escape from host immune response. Blocks the interaction between the host KLRK1 receptor with the ligands ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. The sequestration of diverse KLRK1 ligands in the endoplasmic reticulum and cis-Golgi apparatus of cells by UL16 inhibits the activation of NK cells

Subcellular Location

Host membrane (Single-pass membrane protein)

Subunit

Interacts with host ULBP1, ULBP2 and MICB

Gene: UL16  |  Organism: Human cytomegalovirus (strain AD169)
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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