Recombinant Human Decorin (DCN), partial

Recombinant Human Decorin (DCN), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000481 Category:

Product Specifications

Product SkuBCRECP-000481
Product DescriptionRecombinant Human Decorin (DCN) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 20-359aa. [Accession | P07585].
Uniprot No.P07585
Gene NamesDCN
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-359aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight41.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

May affect the rate of fibrils formation.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix; Secreted
Tissue Specificity: Detected in placenta (at protein level). Detected in cerebrospinal fluid, fibroblasts and urine (at protein level)
Disease Association: Corneal dystrophy, congenital stromal (CSCD) : A corneal dystrophy characterized by congenital corneal opacification consisting of a large number of flakes and spots throughout all layers of the stroma. It results in progressive, painless visual loss. Corneal erosions and photophobia are absent. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Decorin (DCN), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-359aa, with N-terminal 6xHis-tagged tag, molecular weight 41.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

May affect the rate of fibrils formation

Subcellular Location

Secreted, extracellular space, extracellular matrix; Secreted

Disease Association

Corneal dystrophy, congenital stromal (CSCD) : A corneal dystrophy characterized by congenital corneal opacification consisting of a large number of flakes and spots throughout all layers of the stroma. It results in progressive, painless visual loss. Corneal erosions and photophobia are absent. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid, fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717)

Subunit

Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity)

Gene: DCN  |  Organism: Homo sapiens  |  Synonyms: Bone proteoglycan II; PG-S2; PG40
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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