Recombinant Human Decorin (DCN), partial

Recombinant Human Decorin (DCN), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000481 Category:

Product Specifications

Product SkuBCRECP-000481
Product DescriptionRecombinant Human Decorin (DCN) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 20-359aa. [Accession | P07585].
Uniprot No.P07585
Gene NamesDCN
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-359aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight41.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

May affect the rate of fibrils formation.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix; Secreted
Tissue Specificity: Detected in placenta (at protein level). Detected in cerebrospinal fluid, fibroblasts and urine (at protein level)
Disease Association: Corneal dystrophy, congenital stromal (CSCD) : A corneal dystrophy characterized by congenital corneal opacification consisting of a large number of flakes and spots throughout all layers of the stroma. It results in progressive, painless visual loss. Corneal erosions and photophobia are absent. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Decorin (DCN), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 20-359aa, with N-terminal 6xHis-tagged tag, molecular weight 41.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

May affect the rate of fibrils formation

Subcellular Location

Secreted, extracellular space, extracellular matrix; Secreted

Disease Association

Corneal dystrophy, congenital stromal (CSCD) : A corneal dystrophy characterized by congenital corneal opacification consisting of a large number of flakes and spots throughout all layers of the stroma. It results in progressive, painless visual loss. Corneal erosions and photophobia are absent. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid, fibroblasts and urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717)

Subunit

Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity)

Gene: DCN  |  Organism: Homo sapiens  |  Synonyms: Bone proteoglycan II; PG-S2; PG40
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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