Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 42.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial — Catalyzes the de novo synthesis of acetyl-CoA in vitro. Purity >90%.

SKU: BCRECP-000508 Category:
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Product Specifications

Product SkuBCRECP-000508
Product DescriptionRecombinant Human Disco-interacting protein 2 homolog A (DIP2A) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 9-127aa. [Accession | Q14689].
Uniprot No.Q14689
Gene NamesDIP2A
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region9-127aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight42.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Catalyzes the de novo synthesis of acetyl-CoA in vitro. Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission. Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes.

Biological Context

Subcellular Location: Cell membrane (Peripheral membrane protein); Mitochondrion; Cell projection, dendritic spine
Tissue Specificity: Low expression in all tissues tested

Product Specifications

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 9-127aa, with C-terminal hFc1-tagged tag, molecular weight 42.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002)

Subcellular Location

Cell membrane (Peripheral membrane protein); Mitochondrion; Cell projection, dendritic spine

Tissue Specificity

Low expression in all tissues tested

Subunit

Interacts with FSTL1; DIP2A may act as a cell surface receptor for FSTL1 (PubMed:20054002, PubMed:20860622). Interacts (via N-terminus) with CTTN (via SH3 domain); the interaction promotes acetylation of CTTN and is required for proper synaptic transmission (By similarity). Interacts with SHANK3 (By similarity)

Gene: DIP2A  |  Organism: Homo sapiens
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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