Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial, Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 42.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial — Catalyzes the de novo synthesis of acetyl-CoA in vitro. Purity >90%.

SKU: BCRECP-000508 Category:
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Product Specifications

Product SkuBCRECP-000508
Product DescriptionRecombinant Human Disco-interacting protein 2 homolog A (DIP2A) Protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 9-127aa. [Accession | Q14689].
Uniprot No.Q14689
Gene NamesDIP2A
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region9-127aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight42.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Catalyzes the de novo synthesis of acetyl-CoA in vitro. Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission. Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes.

Biological Context

Subcellular Location: Cell membrane (Peripheral membrane protein); Mitochondrion; Cell projection, dendritic spine
Tissue Specificity: Low expression in all tissues tested

Product Specifications

Recombinant Human Disco-interacting protein 2 homolog A (DIP2A), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 9-127aa, with C-terminal hFc1-tagged tag, molecular weight 42.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002)

Subcellular Location

Cell membrane (Peripheral membrane protein); Mitochondrion; Cell projection, dendritic spine

Tissue Specificity

Low expression in all tissues tested

Subunit

Interacts with FSTL1; DIP2A may act as a cell surface receptor for FSTL1 (PubMed:20054002, PubMed:20860622). Interacts (via N-terminus) with CTTN (via SH3 domain); the interaction promotes acetylation of CTTN and is required for proper synaptic transmission (By similarity). Interacts with SHANK3 (By similarity)

Gene: DIP2A  |  Organism: Homo sapiens
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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