Recombinant Human DNA cross-link repair 1A protein (DCLRE1A), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 4.1kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human DNA cross-link repair 1A protein (DCLRE1A), partial

Recombinant Human DNA cross-link repair 1A protein (DCLRE1A), partial — May be required for DNA interstrand cross-link repair. Purity >85%.

SKU: BCRECP-000480 Category:
Online Inquiry →

Product Specifications

Product SkuBCRECP-000480
Product DescriptionRecombinant Human DNA cross-link repair 1A protein (DCLRE1A) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 690-1040aa. [Accession | Q6PJP8].
Uniprot No.Q6PJP8
Gene NamesDCLRE1A
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region690-1040aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight4.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle

Product Specifications

Recombinant Human DNA cross-link repair 1A protein (DCLRE1A), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 690-1040aa, with N-terminal 6xHis-tagged tag, molecular weight 4.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin (PubMed:31434986). Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem) (PubMed:31434986)

Subcellular Location

Nucleus

Tissue Specificity

Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle

Subunit

Binds constitutively to TP53BP1. Binds CDC27, which is itself a component of the anaphase promoting complex (APC). Binds PIAS1

Gene: DCLRE1A  |  Organism: Homo sapiens  |  Synonyms: Beta-lactamase DCLRE1A; SNM1 homolog A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top