Recombinant Human Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 55.3kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)

Recombinant Human Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) — Dual specificity kinase. Purity >90%.

SKU: BCRECP-001121 Categories: , ,
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Product Specifications

Product SkuBCRECP-001121
Product DescriptionRecombinant Human Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 1-347aa. [Accession | P46734].
Uniprot No.P46734
Gene NamesMAP2K3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-347aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight55.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Biological Context

Tissue Specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues
Disease Association: [Defects in MAP2K3 may be involved in colon cancer]

Product Specifications

Recombinant Human Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-347aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 55.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14

Disease Association

[Defects in MAP2K3 may be involved in colon cancer]

Tissue Specificity

Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues

Subunit

(Microbial infection) Interacts with Yersinia YopJ

Gene: MAP2K3  |  Organism: Homo sapiens  |  Synonyms: MAPK/ERK kinase 3; Stress-activated protein kinase kinase 2
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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