Recombinant Human E3 ubiquitin-protein ligase SMURF2 (SMURF2), Homo sapiens (Human), E.coli, N-terminal GST-tagged, 113.2kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human E3 ubiquitin-protein ligase SMURF2 (SMURF2)

Recombinant Human E3 ubiquitin-protein ligase SMURF2 (SMURF2) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-001671 Categories: ,
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Product Specifications

Product SkuBCRECP-001671
Product DescriptionRecombinant Human E3 ubiquitin-protein ligase SMURF2 (SMURF2) Protein is expressed from E.coli with N-terminal GST-tagged. It contains 1-748aa. [Accession | Q9HAU4].
Uniprot No.Q9HAU4
Gene NamesSMURF2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-748aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal GST-tagged
Molecular weight113.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

(Microbial infection) In case of filoviruses Ebola/EBOV and Marburg/MARV infection, the complex formed by viral matrix protein VP40 and SMURF2 facilitates virus budding.

Biological Context

Subcellular Location: Nucleus; Cytoplasm; Cell membrane; Membrane raft
Tissue Specificity: Widely expressed
Pathway: Protein modification; protein ubiquitination

Product Specifications

Recombinant Human E3 ubiquitin-protein ligase SMURF2 (SMURF2) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-748aa, with N-terminal GST-tagged tag, molecular weight 113.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) In case of filoviruses Ebola/EBOV and Marburg/MARV infection, the complex formed by viral matrix protein VP40 and SMURF2 facilitates virus budding

Subcellular Location

Nucleus; Cytoplasm; Cell membrane; Membrane raft

Tissue Specificity

Widely expressed

Subunit

(Microbial infection) Interacts (via WW domains) with EBOV and MARV VP40 (via PPXY motif); the interaction facilitates VP40 virus-like particle budding

Pathway

Protein modification; protein ubiquitination

Gene: SMURF2  |  Organism: Homo sapiens  |  Synonyms: HECT-type E3 ubiquitin transferase SMURF2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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