Recombinant Human Endothelin-3 (EDN3), Homo sapiens (Human), Yeast, C-terminal 6xHis-Myc-tagged, 7.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Endothelin-3 (EDN3)

Recombinant Human Endothelin-3 (EDN3) — recombinant protein from Homo sapiens (Human), expressed in Yeast. Purity >85%.

SKU: BCRECP-000558 Category:
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Product Specifications

Product SkuBCRECP-000558
Product DescriptionRecombinant Human Endothelin-3 (EDN3) Protein is expressed from Yeast with C-terminal 6xHis-Myc-tagged. It contains 97-117aa. [Accession | P14138].
Uniprot No.P14138
Gene NamesEDN3
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region97-117aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-Myc-tagged
Molecular weight7.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Endothelins are endothelium-derived vasoconstrictor peptides.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells
Disease Association: Hirschsprung disease 4 (HSCR4) : A disorder of neural crest development characterized by absence of enteric ganglia along a variable length of the intestine. It is the most common cause of congenital intestinal obstruction. Early symptoms range from complete acute neonatal obstruction, characterized by vomiting, abdominal distention and failure to pass stool, to chronic constipation in the older child. [The disease is caused by variants affecting the gene represented in this entry] | Waardenburg syndrome 4B (WS4B) : A disorder characterized by the association of Waardenburg features (depigmentation and deafness) with the absence of enteric ganglia in the distal part of the intestine (Hirschsprung disease). [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Endothelin-3 (EDN3) is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 97-117aa, with C-terminal 6xHis-Myc-tagged tag, molecular weight 7.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Endothelins are endothelium-derived vasoconstrictor peptides

Subcellular Location

Secreted

Disease Association

Hirschsprung disease 4 (HSCR4) : A disorder of neural crest development characterized by absence of enteric ganglia along a variable length of the intestine. It is the most common cause of congenital intestinal obstruction. Early symptoms range from complete acute neonatal obstruction, characterized by vomiting, abdominal distention and failure to pass stool, to chronic constipation in the older child. [The disease is caused by variants affecting the gene represented in this entry] | Waardenburg syndrome 4B (WS4B) : A disorder characterized by the association of Waardenburg features (depigmentation and deafness) with the absence of enteric ganglia in the distal part of the intestine (Hirschsprung disease). [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells

Gene: EDN3  |  Organism: Homo sapiens  |  Synonyms: Preproendothelin-3

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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