Recombinant Human Estrogen receptor beta (ESR2), partial, Homo sapiens (Human), Yeast, N-terminal 6xHis-tagged, 61.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Estrogen receptor beta (ESR2), partial

Recombinant Human Estrogen receptor beta (ESR2), partial — recombinant protein from Homo sapiens (Human), expressed in Yeast. Purity >90%.

SKU: BCRECP-000610 Category:
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Product Specifications

Product SkuBCRECP-000610
Product DescriptionRecombinant Human Estrogen receptor beta (ESR2) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 2-530aa. [Accession | Q92731].
Uniprot No.Q92731
Gene NamesESR2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region2-530aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight61.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasTranscription

Function

Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: Expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain
Disease Association: Ovarian dysgenesis 8 (ODG8) : An autosomal dominant form of ovarian dysgenesis, a disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads. [The disease may be caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Estrogen receptor beta (ESR2), partial is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 2-530aa, with N-terminal 6xHis-tagged tag, molecular weight 61.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability

Subcellular Location

Nucleus

Disease Association

Ovarian dysgenesis 8 (ODG8) : An autosomal dominant form of ovarian dysgenesis, a disorder characterized by lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism as a result of streak gonads. [The disease may be caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain

Subunit

Preferentially forms a heterodimer with ESR1 rather than ESR2 isoform 1 and inhibits DNA-binding by ESR1

Gene: ESR2  |  Organism: Homo sapiens  |  Synonyms: Nuclear receptor subfamily 3 group A member 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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