Recombinant Human F-box only protein 3 (FBXO3), Homo sapiens (Human), Yeast, N-terminal 6xHis-tagged, 56.6kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human F-box only protein 3 (FBXO3)

Recombinant Human F-box only protein 3 (FBXO3) — (Microbial infection) Associates with the Rift valley fever virus NSs to form a remodeled E3 ligase that triggers efficient proteasomal degradation of targeted proteins. Purity >90%.

SKU: BCRECP-000638 Category:
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Product Specifications

Product SkuBCRECP-000638
Product DescriptionRecombinant Human F-box only protein 3 (FBXO3) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 1-471aa. [Accession | Q9UK99].
Uniprot No.Q9UK99
Gene NamesFBXO3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region1-471aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight56.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

(Microbial infection) Associates with the Rift valley fever virus NSs to form a remodeled E3 ligase that triggers efficient proteasomal degradation of targeted proteins. The filamentous E3 ligase targets the TFIIH complex leading to robust inhibition of antiviral immunity and enhances viral pathogenesis.

Biological Context

Subcellular Location: Nucleus
Pathway: Protein modification; protein ubiquitination

Product Specifications

Recombinant Human F-box only protein 3 (FBXO3) is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 1-471aa, with N-terminal 6xHis-tagged tag, molecular weight 56.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

(Microbial infection) Associates with the Rift valley fever virus NSs to form a remodeled E3 ligase that triggers efficient proteasomal degradation of targeted proteins. The filamentous E3 ligase targets the TFIIH complex leading to robust inhibition of antiviral immunity and enhances viral pathogenesis

Subcellular Location

Nucleus

Subunit

(Microbial infection) Interacts (via ApaG domain) with Rift valley fever virus NSs helical filament; this interaction forms a filamentous E3 which mediates degradation of TFIIH complex through interaction with GT2H1

Pathway

Protein modification; protein ubiquitination

Gene: FBXO3  |  Organism: Homo sapiens
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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