Recombinant Human Follistatin-related protein 1 (FSTL1), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-GST-tagged, 43.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Follistatin-related protein 1 (FSTL1), partial

Recombinant Human Follistatin-related protein 1 (FSTL1), partial — Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Purity >90%.

SKU: BCRECP-000697 Category:
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Product Specifications

Product SkuBCRECP-000697
Product DescriptionRecombinant Human Follistatin-related protein 1 (FSTL1) Protein is expressed from E.coli with N-terminal 6xHis-GST-tagged. It contains 176-285aa. [Accession | Q12841].
Uniprot No.Q12841
Gene NamesFSTL1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region176-285aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-GST-tagged
Molecular weight43.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Overexpressed in synovial tissues from rheumatoid arthritis

Product Specifications

Recombinant Human Follistatin-related protein 1 (FSTL1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 176-285aa, with N-terminal 6xHis-GST-tagged tag, molecular weight 43.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (PubMed:22265692, PubMed:29212066). Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692)

Subcellular Location

Secreted

Tissue Specificity

Overexpressed in synovial tissues from rheumatoid arthritis (PubMed:15638044)

Subunit

Homodimer (By similarity). Interacts with SCN10A (By similarity). Interacts with DIP2A; DIP2A may act as a cell surface receptor for FSTL1 (PubMed:20054002, PubMed:20860622). Interacts with BMP4 (PubMed:29212066). Interacts with CD14; this interaction promotes TL4-mediated signaling cascade (PubMed:22265692)

Gene: FSTL1  |  Organism: Homo sapiens  |  Synonyms: Follistatin-like protein 1
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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