Recombinant Human Fractalkine (CX3CL1), partial, Biotinylated, Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-Avi-tagged, 38.5kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Fractalkine (CX3CL1), partial, Biotinylated

Recombinant Human Fractalkine (CX3CL1), partial, Biotinylated — (Microbial infection) Mediates the cytoadherence of erythrocytes infected with parasite P. Purity >95%.

SKU: BCRECP-000459 Categories: ,
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Product Specifications

Product SkuBCRECP-000459
Product DescriptionRecombinant Human Fractalkine (CX3CL1) Protein is expressed from Mammalian cell with C-terminal 10xHis-Avi-tagged. It contains 25-341aa. [Accession | P78423].
Uniprot No.P78423
Gene NamesCX3CL1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region25-341aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-Avi-tagged
Molecular weight38.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Adhesion

Function

(Microbial infection) Mediates the cytoadherence of erythrocytes infected with parasite P.falciparum (strain 3D7) with endothelial cells by interacting with P.falciparum CBP1 and CBP2 expressed at the surface of erythrocytes. The adhesion prevents the elimination of infected erythrocytes by the spleen (Probable).

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Most abundant in the brain and heart

Product Specifications

Recombinant Human Fractalkine (CX3CL1), partial, Biotinylated is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 25-341aa, with C-terminal 10xHis-Avi-tagged tag, molecular weight 38.5kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Mediates the cytoadherence of erythrocytes infected with parasite P.falciparum (strain 3D7) with endothelial cells by interacting with P.falciparum CBP1 and CBP2 expressed at the surface of erythrocytes (PubMed:27653778). The adhesion prevents the elimination of infected erythrocytes by the spleen (Probable)

Subcellular Location

Secreted

Tissue Specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. Most abundant in the brain and heart

Subunit

(Microbial infection) Interacts with P.falciparum (strain 3D7) CBP1 and CBP2 (via their extracellular domains); the interaction mediates the adhesion of infected erythrocytes with endothelial cells

Gene: CX3CL1  |  Organism: Homo sapiens  |  Synonyms: C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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