Function
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Product Specifications
Recombinant Human Growth-regulated alpha protein (CXCL1) (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 35-107aa, with C-terminal 10xHis-tagged tag, molecular weight 9.2 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Chemokine proteins →
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Mouse Vegfa at 2 μg/mL can bind Mouse Kdr. The EC50 is 12.64-13.88 ng/mL.;Recombinant Mouse Kdr captured on Protein A Chip can bind Recombinant Mouse Vegfa with an affinity constant of 3.24 nM as detected by MetaSPR Assay (WeSPRTM 200).
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
