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Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active)

Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000645 Categories: , ,
Product SKUBCACP-000645
Product DescriptionRecombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1) protein is expressed from Mammalian cell with N-terminal 10xHis-tagged. It contains 21-295aa. [Accession | Q96D42].
Uniprot No.Q96D42
Gene NamesHAVCR1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region21-295aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight30.9 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human TRBC1 at 2 μg/mL can bind Anti-TRBC1 recombinant antibody . The EC50 is 2.977-3.524 ng/mL.;TRBC1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human TRBC1 with an affinity constant of 3.48 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1; CD antigen CD365

Function

(Microbial infection) Plays a positive role in Chikungunya virus cell entry.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cell projection, phagocytic cup; Cytoplasmic vesicle, phagosome
Tissue Specificity: Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses

Product Specifications

Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 21-295aa, with N-terminal 10xHis-tagged tag, molecular weight 30.9 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

(Microbial infection) Plays a positive role in Chikungunya virus cell entry

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell projection, phagocytic cup; Cytoplasmic vesicle, phagosome

Tissue Specificity

Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses

Subunit

(Microbial infection) Interacts with Zika virus envelope protein E

Gene: HAVCR1  |  Organism: Homo sapiens  |  Synonyms: Kidney injury molecule 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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