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Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active)

Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000645 Categories: , ,
Product SKUBCACP-000645
Product DescriptionRecombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1) protein is expressed from Mammalian cell with N-terminal 10xHis-tagged. It contains 21-295aa. [Accession | Q96D42].
Uniprot No.Q96D42
Gene NamesHAVCR1
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region21-295aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight30.9 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human TRBC1 at 2 μg/mL can bind Anti-TRBC1 recombinant antibody . The EC50 is 2.977-3.524 ng/mL.;TRBC1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human TRBC1 with an affinity constant of 3.48 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1; CD antigen CD365

Function

(Microbial infection) Plays a positive role in Chikungunya virus cell entry.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cell projection, phagocytic cup; Cytoplasmic vesicle, phagosome
Tissue Specificity: Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses

Product Specifications

Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 21-295aa, with N-terminal 10xHis-tagged tag, molecular weight 30.9 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TRBC1 at 2 μg/mL can bind Anti-TRBC1 recombinant antibody . The EC50 is 2.977-3.524 ng/mL.;TRBC1 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human TRBC1 with an affinity constant of 3.48 nM as detected by MetaSPR Assay (WeSPRTM 200).

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

(Microbial infection) Plays a positive role in Chikungunya virus cell entry

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell projection, phagocytic cup; Cytoplasmic vesicle, phagosome

Tissue Specificity

Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses

Subunit

(Microbial infection) Interacts with Zika virus envelope protein E

Gene: HAVCR1  |  Organism: Homo sapiens  |  Synonyms: Kidney injury molecule 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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