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Recombinant Human Hepatocyte growth factor (HGF), partial (Active)

Recombinant Human Hepatocyte growth factor (HGF), partial (Active) — Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Purity >95%.

SKU: BCACP-001132 Categories: ,
Product SKUBCACP-001132
Product DescriptionRecombinant Human Hepatocyte growth factor (HGF) protein is expressed from Mammalian cell with Tag free. It contains 32-494aa&495-728aa. [Accession | P14210].
Uniprot No.P14210
Gene NamesHGF
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region32-494aa&495-728aa
SpeciesHomo sapiens (Human)
Tag InfoTag free
Molecular weight53.7 kDa ( α chain), 26 kDa ( β chain)
ActivityMeasured in a cell proliferation assay using TF-1 cells, The ED50 for this effect is ≤ 0.2 ng/mL,orresponding to a specific activity of > 1x 10^7 units/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesHepatocyte growth factor; HPTA; HGF; SF; Scatter factor; Hepatopoietin-A

Function

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.

Product Specifications

Recombinant Human Hepatocyte growth factor (HGF), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 32-494aa&495-728aa, with Tag free tag, molecular weight 53.7 kDa ( α chain), 26 kDa ( β chain), purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured in a cell proliferation assay using TF-1 cells, The ED50 for this effect is ≤ 0.2 ng/mL,orresponding to a specific activity of > 1x 10^7 units/mg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:15167892, PubMed:20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675)

Gene: HGF  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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