Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial, Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 33.0kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial

Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial — Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Purity >85%.

SKU: BCRECP-002831 Categories: ,
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Product Specifications

Product SkuBCRECP-002831
Product DescriptionRecombinant Human herpesvirus 1 Envelope glycoprotein C (gC) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 250-480aa. [Accession | P10228].
Uniprot No.P10228
Gene NamesgC
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region250-480aa
SpeciesHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight33.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays several roles in host immune evasion by inhibiting the host complement cascade activation, and by providing a shield against neutralizing antibodies that interfere with gB-gD, gB-gH/gL or gD-gH/gL interactions.

Biological Context

Subcellular Location: Virion membrane (Single-pass membrane protein)

Product Specifications

Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial is a recombinant protein from Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1), expressed in E.coli, covering amino acids 250-480aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 33.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays several roles in host immune evasion by inhibiting the host complement cascade activation, and by providing a shield against neutralizing antibodies that interfere with gB-gD, gB-gH/gL or gD-gH/gL interactions (By similarity)

Subcellular Location

Virion membrane (Single-pass membrane protein)

Subunit

Interacts with host complement component C3b; this interaction inhibits host immune response by disregulating complement cascade

Gene: gC  |  Organism: Human herpesvirus 1 (strain 17)

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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