Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial, Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 33.0kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial

Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial — Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Purity >85%.

SKU: BCRECP-002831 Categories: ,
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Product Specifications

Product SkuBCRECP-002831
Product DescriptionRecombinant Human herpesvirus 1 Envelope glycoprotein C (gC) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 250-480aa. [Accession | P10228].
Uniprot No.P10228
Gene NamesgC
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region250-480aa
SpeciesHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight33.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays several roles in host immune evasion by inhibiting the host complement cascade activation, and by providing a shield against neutralizing antibodies that interfere with gB-gD, gB-gH/gL or gD-gH/gL interactions.

Biological Context

Subcellular Location: Virion membrane (Single-pass membrane protein)

Product Specifications

Recombinant Human herpesvirus 1 Envelope glycoprotein C (gC), partial is a recombinant protein from Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1), expressed in E.coli, covering amino acids 250-480aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 33.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays several roles in host immune evasion by inhibiting the host complement cascade activation, and by providing a shield against neutralizing antibodies that interfere with gB-gD, gB-gH/gL or gD-gH/gL interactions (By similarity)

Subcellular Location

Virion membrane (Single-pass membrane protein)

Subunit

Interacts with host complement component C3b; this interaction inhibits host immune response by disregulating complement cascade

Gene: gC  |  Organism: Human herpesvirus 1 (strain 17)

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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