Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM), Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 93.4kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM) — Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Purity >90%.

SKU: BCRECP-000849 Category:
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Product Specifications

Product SkuBCRECP-000849
Product DescriptionRecombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 2-730aa. [Accession | P52272].
Uniprot No.P52272
Gene NamesHNRNPM
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-730aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight93.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

Biological Context

Subcellular Location: Nucleus, nucleolus

Product Specifications

Recombinant Human Heterogeneous nuclear ribonucleoprotein M (HNRNPM) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2-730aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 93.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines

Subcellular Location

Nucleus, nucleolus

Subunit

Identified in the spliceosome C complex (PubMed:11991638). Interacts with PPIA/CYPA (PubMed:25678563)

Gene: HNRNPM  |  Organism: Homo sapiens
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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