Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 76.0 kDa, purity >95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
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Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active)

Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active) — Inactive tyrosine kinase involved in the Wnt signaling pathway. Purity >95%.

SKU: BCACP-000307 Categories: , ,
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Product SKUBCACP-000307
Product DescriptionRecombinant Human Inactive tyrosine-protein kinase 7(PTK7) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 31-704aa. [Accession | Q13308].
Uniprot No.Q13308
Gene NamesPTK7
PurityGreater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region31-704aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight76.0 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 at 5 μg/mL on an Nickel Coated plate can bind Anti-CLDN18.2 recombinant antibody , the EC50 is 0.4640-0.6372 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesColon carcinoma kinase 4 (CCK-4); Protein-tyrosine kinase 7;Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7

Function

Inactive tyrosine kinase involved in the Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathways. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.

Product Specifications

Recombinant Human Inactive tyrosine-protein kinase 7(PTK7),partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 31-704aa, with C-terminal 10xHis-tagged tag, molecular weight 76.0 kDa, purity Greater than 95% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN18.2 at 5 μg/mL on an Nickel Coated plate can bind Anti-CLDN18.2 recombinant antibody , the EC50 is 0.4640-0.6372 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Inactive tyrosine kinase involved in the Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathways. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Does not bind ATP (PubMed:24107129, PubMed:32619402)

Gene: PTK7  |  Organism: Homo sapiens

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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